The crash took place on the A22 in Golden Cross at around 11am today.
Two cars are believed to be involved with one witness reporting that a car had been "on fire".
Air ambulances as well as emergency services are currently on the scene.
Sussex Police have been approached for comment.
![Car ‘set on fire’ following two vehicle collision in East Sussex village](https://www.sussexexpress.co.uk/webimg/b25lY21zOmNkODg0ODMyLTliYzgtNDE1NC05MDA0LTcxNzI3NjE3ZWM3NTplOGFiNzhlOS1jNDBhLTQzNzUtODFmOS1iY2E0M2I2MWEwNjM=.jpg?crop=3:2&trim=&width=640)
1. Car ‘set on fire’ following two vehicle collision in East Sussex village
Car ‘set on fire’ following two vehicle collision in East Sussex villagePhoto: Sussex News and Pictures
![Car ‘set on fire’ following two vehicle collision in East Sussex village](https://www.sussexexpress.co.uk/webimg/b25lY21zOjk2ZjJlZjJhLWU3YTQtNGE1Ni04ZGFkLWM0NmYwZDc4YThlYzoyMzczZDFjNy05MThjLTRiYWQtOGEwNy1kZWU1MTRjMzlkZTY=.jpg?crop=3:2&trim=&width=640)
2. Car ‘set on fire’ following two vehicle collision in East Sussex village
Car ‘set on fire’ following two vehicle collision in East Sussex villagePhoto: Sussex News and Pictures
![Car ‘set on fire’ following two vehicle collision in East Sussex village](https://www.sussexexpress.co.uk/webimg/b25lY21zOjg2YzlhOTc0LTdiYzktNDc2ZC1hYWQ5LTJmZmY0MjYyNWM2MjoyZWRlY2Y0ZS0wYjQ4LTQ5OWUtYjIzNS1lZGQwNmM1NzMxYTU=.jpg?crop=3:2&trim=&width=640)
3. Car ‘set on fire’ following two vehicle collision in East Sussex village
Car ‘set on fire’ following two vehicle collision in East Sussex villagePhoto: Sussex News and Pictures
![Car ‘set on fire’ following two vehicle collision in East Sussex village](https://www.sussexexpress.co.uk/webimg/b25lY21zOmViYzk4ODQyLTgxZDYtNDk5MC1hZGQ5LWE5NDhmZTJmZmI2ODo2MjliYjBjMS04N2I2LTRiOWYtYjIxOC05Nzc2ZjBlYTQwMDM=.jpg?crop=3:2&trim=&width=640)
4. Car ‘set on fire’ following two vehicle collision in East Sussex village
Car ‘set on fire’ following two vehicle collision in East Sussex villagePhoto: Sussex News and Pictures